Industrial Biotechnology

09
Featured Session · 09 of 35

Industrial Biotechnology

Industrial biotechnology is central to the bioeconomy transition, replacing petrochemical processes with engineered microbial routes for fuels, materials, and chemicals. GSBG 2027 will cover directed evolution and machine-learning-guided enzyme design for plastic depolymerization (PETase, MHETase, FAST-PETase), CO2-fixing chemolithoautotrophs (LanzaTech), and engineered yeast for cannabinoids, opioids, and rare natural products. Sessions will examine continuous bioprocessing, downstream purification advances (single-pass tangential flow, magnetic bead capture), digital twins for bioreactor control, and the scale-up bottlenecks that determine whether a strain in flask becomes a 200,000-liter commercial product.

Topics covered in this session
  • PET-degrading enzymes: PETase, FAST-PETase, leaf-branch compost cutinase
  • Gas fermentation: LanzaTech, Kiverdi for CO and CO2 valorization
  • Engineered yeast for cannabinoids, opioids, and terpenoids
  • Directed evolution and ML-guided enzyme engineering
  • Continuous downstream processing and single-use bioreactors
  • Digital twins and process analytical technology (PAT)
  • Techno-economic analysis and scale-up from bench to commercial